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First African Workshop on Virus
Evolution and Molecular Epidemiology
the South African HIV/AIDS Treatment Management
and the Seminar on Phylogenetics Evolution and HIV.
2 to 11 of July 2003, Durban and Cape Town, South Africa.
Organized by: Sharon Cassol, Chris Seebregts,
Karen Bishop and Tulio de Oliveira
" The above workshops was a great
success with students and lectures learning about evolution,
epidemiology and the management of HIV molecular data.
After long days of intense concetration, the workshop participants
enjoyed socializing in the evening at Durban bars and restaurants ..."
The Wellcomme Trust (#061238 )
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The
Nelson R Mandela School of Medicine
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The
Southern Africa Medical Research Council
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The
Flanders
Bilateral Proposal
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Workshop snapshops
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Workshop Program:
Day 1 (2 of July):
- Overview
of HIV-1 Molecular Research in Kwazulu-Natal, South Africa.
- Fundamentals
of molecular evolution.
- Alignment
algorithms.
- Database
homology searching. Practical computer session.
Day 2 (3 of July):
- Methods
for construction of phylogenetic trees - I and II Theoretical Lecture.
- Construction
and interpretation of phylogenetic trees - I. Practical computer
session using Bioedit, Clustal, Phylip.
Day 3 (4 of July):
- Modeling
nucleotide substitution.
- Phylogenetic
signal and phylogenetic noise in sequence data.
- An
integrated LINUX environment for molecular phylogenetic analyses.
Theoretical and practical session.
Day 4 (5 of July):
- Construction
and interpretation of phylogenetic trees - II. Maximum likelihood
applications.
- Construction
and interpretation of phylogenetic trees - III. Practical computer
session using PAUP*, Dambe, Mega
- Detecting
recombination in viral sequences. Theoretical and Pratical lecture.
- The
Different HIV-1 subype epidemic potential in Brazil and South Africa.
Day 5: (HIV/AIDS Treatment management workshop)
- HIV
drug resistance testing in clinical practice. Basic concepts and
practical applications
- Drug
Resistance Genotyping and Therapeutic Monitoring in KwaZulu-Natal,
South Africa
- HIV/AIDS
treatment in South Africa
- HIV/AIDS
treatment and drug resistance in Brazil, a successful case using
antiretroviral generic drugs.
- Rega
V6.0: a clinically-relevant drug resistance interpretation system
Day 6: (11 of July) - The Seminar on Phylogenetics Evolution and HIV
(at MRC Cape Town)
- Phylogenetics,
Past, Present and Future
- Host,
Pathogen and Selection
- Advanced
Methods for Phylogenetic Analysis (Maximum Likelihood, Bayesian, Split
Decomposition methods)
- Detecting
Positive Selection in HIV-1 Molecular Sequences
- Molecular
Epidemiology of HIV-1 in South Africa: 1984 to 2003
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Workshop Lectures:
- Sharon Cassol, PhD
- Patrick
Charls, CCA
- Jerry
Coovadia, MD
- Tulio de
Oliveira, PhD
- Susan Engelbrecht,
PhD
- Walter Fitch,
PhD
- Michelle Gordon, MSc
- Philippe
Lemey
- Marco Salemi, PhD
- Mika Salminem,
PhD
- Amilcar Tanuri, PhD
- Anne-Mieke
VanDamme, PhD
- Sonia van
Dooren,
- Kristel
Van Laethem, PhD
- Winston Hide, PhD
Participants:
- Sabri Al-Sanabani, PhD
- Helba Bredell
- Stefano Butto, PhD
- Anna Badimo
- Karen
Bishop
- Polan Chetty
- M. Aslam Sathar, PhD
- Edana
Cassol
- Mia Coetzer
- Paul
Chelule,
PhD
- Ryan
Doherty
- Siva
Danaviah
- T. Jonathan Edwards
- Jandre Grobler
- Natalie
Graham
- Andre Loxton
- Alasdair
Leslie
- Busisiwe Monosi
- Maria Paximadis, PhD
- Roger Phili
- Taryn Page
- Oubaas Pretorius, PhD
- Maria Jose Ruiz Alvarez, PhD
- Chris Seebregts, PhD
- Venessa Timmelman
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