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HIV Data Management and Data
Mining for Antiretroviral Drug
Resistance Research.
13 to 16 of December 2004, Durban, South Africa.
Organized
by: Sharon Cassol, Michelle Gordon and Tulio de Oliveira
Molecular
Virology and Bioinformatics Unit at Africa Centre for Health and Population
Studies
" Introduction: "
Deadline for application: 22 of November, 2004.
Lectures:
| Anne-Mieke Vandamme |
Ph.D., Professor in Evolutionary Genetics at the Katholieke
Universiteit Leuven, Belgium. |
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Sharon Cassol
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PhD, Professor in
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Hendrix
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PhD, Professor in ???
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Nigel Rollins
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PhD, Professor
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Tulio de Oliveira
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PhD, Post Doc researcher
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Michelle Gordon
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Koen
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Chris Seegbrets
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Koen
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Jan
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Funders:
The Wellcomme Trust (#061238 )
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The
Nelson R Mandela School of Medicine
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The
Southern Africa Medical Research Council
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The
Flanders Bilateral Proposal
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Workshop Program:
Day 1 (2 of July):
- Overview
of HIV-1 Molecular Research in Kwazulu-Natal,
South Africa.
- Fundamentals
of molecular evolution.
- Alignment
algorithms.
- Database
homology searching. Practical computer session.
Day 2 (3 of July):
- Methods
for construction of phylogenetic trees - I and
II Theoretical Lecture.
- Construction
and interpretation of phylogenetic trees - I.
Practical computer session using Bioedit, Clustal,
Phylip.
Day 3 (4 of July):
- Modeling
nucleotide substitution.
- Phylogenetic
signal and phylogenetic noise in sequence data.
- An
integrated LINUX environment for molecular phylogenetic
analyses. Theoretical and practical session.
Day 4 (5 of July):
- Construction
and interpretation of phylogenetic trees - II.
Maximum likelihood applications.
- Construction
and interpretation of phylogenetic trees - III.
Practical computer session using PAUP*, Dambe,
Mega
- Detecting
recombination in viral sequences. Theoretical
and Pratical lecture.
-
The Different HIV-1 subype epidemic potential in Brazil and South Africa.
Day 5: (HIV/AIDS Treatment management workshop)
- HIV
drug resistance testing in clinical practice.
Basic concepts and practical applications
- Drug
Resistance Genotyping and Therapeutic Monitoring
in KwaZulu-Natal, South Africa
- HIV/AIDS
treatment in South Africa
- HIV/AIDS
treatment and drug resistance in Brazil, a successful
case using antiretroviral generic drugs.
- Rega
V6.0: a clinically-relevant drug resistance interpretation
system
Day 6: (11 of July) - The Seminar on Phylogenetics Evolution and HIV
(at MRC Cape Town)
- Phylogenetics,
Past, Present and Future
- Host,
Pathogen and Selection
- Advanced
Methods for Phylogenetic Analysis (Maximum Likelihood,
Bayesian, Split Decomposition methods)
- Detecting
Positive Selection in HIV-1 Molecular Sequences
- Molecular
Epidemiology of HIV-1 in South Africa: 1984 to
2003
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