News:

Here we provide you with news articles, blogs and tweets on the key aspects of our bioinformatics and drug resistance work.

In this new section of the bioafrica.net website, we disseminate printed and online media coverage of our work and its application in everyday life.


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KRISP Papers


Science Editorial: Inhibiting natural killer cells in AIDS

KRISP Papers - 2018-01-04

The human leukocyte antigen (HLA) gene complex varies enormously among individuals and helps explain individual variation in immunity to infectious diseases. Ramsuran et al. (Science 2018) examined data from almost 10,000 HIV infections.

Expression of the HLA-A and -B alleles was associated with higher viral load, reduced CD4+ T cell counts, and accelerated progression to AIDS. Higher levels of HLA-A expression increased expression of HLA-E, which blocks a specific receptor (NKG2A) on the immune cells that normally eliminate virus-infected cells. Thus, targeting NKG2A might provide a therapeutic avenue for HIV treatment. Read Ramsuran et al. 2018 (Open access).

Links:

http://science.sciencemag.org/content/359/6371/86.editor-summary

Publication cited

Green environment and incident depression in South Africa: a geospatial analysis and mental health implications in a resource-limited setting. Tomita A, Vandormael AM, Cuadros D, Di Minin E, Heikinheimo V, Tanser F, Slotow R, Burns JK, Lancet Planetary Health (2017), 1:152?62.

15 minutes, All news...

KRISP at UKZN is reversing brain drain in Africa and achieving scientific excellence!
From KRISP News, date: 2018-04-19

Nature paper: Renewing Felsenstein's phylogenetic bootstrap in the era of big data
From KRISP Papers, date: 2018-04-18

Thought Leadership Workshop on Biomedical Innovation and Entrepreneurship - 10 April 2018, Pretoria, South Africa
From KRISP & TIA News, date: 2018-04-10
15 minutes, All news...


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