Sequence of the env gene of some KwaZulu-Natal, South African strains of HTLV type I. AIDS Res Hum Retroviruses, 15(13): 1229-33 (1999).

Publication Latest Publications

Title: Sequence of the env gene of some KwaZulu-Natal, South African strains of HTLV type I
Authors: Bhigjee AI, Tarin ML, Bill PL, De Oliveira T, York D.
Journal: AIDS Res Hum Retroviruses,15(13):1229-33 (1999)

Journal Impact Factor (I.F.): 2.178
Number of citations (Google Scholar): 7

Abstract

Phylogenetic analysis of HTLV-I suggests three main subtypes, namely, cosmopolitan, Central African, and Australo-Melanesian. HTLV-I is endemic in KwaZulu-Natal, South Africa. However, sequence data on the local strains are limited to the LTR region. The env gene of the local strain was amplified and sequenced from the peripheral blood of five seropositive individuals. Four had HTLV-I-associated myelopathy and one had infective eczema.

The sequence analysis of the env gene showed a greater then 99% homology of the local strains. They were closely related to the North American strains (99.3%), followed by the Japanese strains (98.3-98.9%). Phylogenetic studies linked the local strains to the cosmopolitan subtype. This study provides new sequence data on the env gene of the local HTLV-I strain

Download: Full text paper

Citation: Bhigjee AI, Tarin ML, Bill PL, De Oliveira T, York D. Sequence of the env gene of some KwaZulu-Natal, South African strains of HTLV type I AIDS Res Hum Retroviruses,15(13):1229-33 (1999).


Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration
Journal: EBioMedicine (2017)

High Rates of Transmission of Drug-resistant HIV in Aruba Resulting in Reduced Susceptibility to the WHO Recommended First-line Regimen in Nearly Half of Newly Diagnosed HIV-infected Patients
Journal: Clinical Infectious Diseases (2017)

Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis
Journal: Clinical Infectious Diseases (2017)
All publications...


Page design updated by Tulio de Oliveira, 2013