Introduction: Southern African Treatment and Resistance Network (SATuRN)

SATuRN currently includes 24 research partners in southern Africa that support our initiatives. We have collated over 3,200 resistance genotypes linked to treatment and clinical information and host two of the best HIV drug resistance databases in the world (The Stanford HIV Drug Resistance Database and RegaDB Clinical Management and Drug resistance Database). To advance access to drug resistance testing to patients, providers and programs, we have been working with a network of academics laboratories to develop and implement a cheaper resistance genotype test. We have also delivered training in drug resistance testing and management to nearly 1,000 physician and nurses in southern Africa...

Poster annual workshop: 
Information:


SATuRN annual workshop

Introduction:

SATuRN Mission/Vision

Who We Are: SATuRN Management, Participant Scientists, International Advisory Board, Funders


Drug Resistance Databases & Bioinformatics tools:

SATuRN Stanford HIV Drug Resistance Database (HIVDB) -  Public Drug Resistance Databases in Southern Africa (de Oliveira, Shafer, Seebregts on behalf of SATuRN, Nature, 2010, 464:673).

SATuRN RegaDB Clinical Management Database - A Collaborative Clinical HIV Drug Resistance Database in Southern Africa


Events & Trainning Program:

SATuRN tele-conferences - Integrating in a virtual format failure clinics in southern Africa

6th Southern African HIV / TB Drug Resistance & Clinical Management Workshop, Gaborone, 7-8 November 2011 (DEADLINE for application: 1st October 2011)


Research and Development (R&D):

SATuRN & Life Technologies (ABI) partnership provide a discounted HIV resistance genotyping system
SATuRN 2011 report:
 Articles featured on the SATuRN 2011 Preliminary report:


SATuRN 2011  report



From our collaborators:

A survey of 20 years of primary drug resistance in South Africa

Surveillance of transmitted HIV-1 drug resistance in South African provinces from 2005-2009

HIV drug resistance in first and second line patients in South Africa: EC Free State and Pretoria cohorts

HIV-1 drug resistance at antiretroviral treatment initiation in children previously exposed to single-dose nevirapine

Lopinavir concentration measurement in plasma or hair are helpful to exclude patients with poor adherence to second line regimens in South Africa

Phenotypic resistance to etravirine in an HIV-1 subtype-C background

HIV clinical management: Integrating in a virtual format failure clinics in southern Africa

SATuRN RegaDB drug resistance & clinical management report



Download the SATuRN report in pdf format (6Mb)

SATuRN links:




Southern African Treatment and Resistance Network (SATuRN) website at bioafrica.net/saturn

Comprehensive links to HIV treatment, ARVs and drug resistance at Stanford HIVDB SATURN mirror.

Comprehensive information on antiretroviral therapy in South Africa at the Treatment Action Campaign (TAC) website.

SATuRN report is available at the PEPFAR activities section of the South African US embassy website.

SATuRN databases and activities are published in the South African Department of Health Newsletter (Impilo 2 Dialogues).



Page last updated by Tulio de Oliveira, Lungani Ndwandwe and Justen Manasa